Top DeFi 2.0 Projects 2025

DeFi 2.0 is rewriting the rules of decentralized finance in 2025. In this guide, we explore the most promising projects revolutionizing yield generation, leverage, and on-chain automation.

Pendle: Tokenized Future Yields

Pendle splits yield-bearing tokens into Principal (PT) and Yield (YT) components. This allows users to speculate on or hedge yield changes. Supporting EigenLayer restaked assets and LSTs like stETH and ezETH, Pendle offers advanced fixed-income strategies for DeFi investors.

Ethena: Synthetic Dollar with Native Yield

Ethena’s USDe is a synthetic stablecoin combining ETH staking with perpetual shorting to deliver native yield. While innovative, this mechanism relies heavily on market conditions and introduces systemic risk that users must carefully evaluate.

Lybra: Yield-Bearing Stablecoins

Lybra issues eUSD, a stablecoin backed by LSDs like stETH, automatically earning staking rewards. Users can borrow, earn, and hold eUSD to maintain exposure to ETH yield while accessing DeFi-native liquidity.

Gearbox: Leverage-as-a-Service

Gearbox enables users to obtain leverage and deploy it across protocols such as Curve, Yearn, and Convex. By separating lenders (passive yield) and borrowers (active DeFi traders) via its efficient Credit Account design, Gearbox delivers flexible, composable leverage.

Mellow Protocol: Automated DeFi Strategies

Mellow lets users create or deposit into permissionless, structured vaults using LSTs and LRTs. Think of it as an Enzyme or Set Protocol reimagined for the EigenLayer era - fully on-chain and open to all.

Key Risks to Keep in Mind

FAQ: DeFi 2.0 in 2025

Is DeFi 2.0 safe?
While highly innovative, DeFi 2.0 protocols typically carry more risk than traditional DeFi. Always do your own research (DYOR), assess smart contract audits, and manage your exposure carefully.
How can I participate in Pendle or Ethena?
You can use supported wallets and staking platforms like Lido and EigenLayer, or interact directly via their dApps. Always verify contract addresses and use official links.
Is yield sustainable in 2025?
Mechanisms like restaking and synthetic leverage create attractive yields, but sustainability depends on protocol adoption, market volatility, and systemic risks inherent to DeFi 2.0 models.